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Zika Vaccine Clinical Trial Underway

The first of a series of clinical trials testing inactivated Zika particles as a vaccine to protect against the live Zika virus is recruiting participants. . . . → Read More: Zika Vaccine Clinical Trial Underway

Health Agency Funds Drug-Resistant Bacteria R&D

Biomedical Advanced Research and Development Authority, or BARDA, signed agreements worth $67 million to develop new treatments and diagnostics for urgent drug-resistant infections. . . . → Read More: Health Agency Funds Drug-Resistant Bacteria R&D

Influenza A Therapy Shown Working in Trial

Electron-microscope image of the 2009 H1N1 influenza virus (CDC.gov)

5 October 2015. A clinical trial testing a synthetic antibody designed to treat influenza A shows the treatment is effective in reducing the spread of flu viruses in humans. Visterra Inc., the therapy’s designer, also received a contract valued as much as $204.5 million from . . . → Read More: Influenza A Therapy Shown Working in Trial

Regeneron to Develop Antibody Therapy for Ebola

Scanning electron micrograph shows Ebola virus budding on monkey kidney cells (Defense.gov)

21 September 2015. Regeneron Pharmaceuticals Inc. received a contract from the U.S. Department of Health and Human Services to develop an engineered antibody designed to treat Ebola infections. The initial $17 million contract from HHS’s Biomedical Advanced Research and Development Authority or . . . → Read More: Regeneron to Develop Antibody Therapy for Ebola

Ebola-Marburg Vaccine Development, Testing Contract Awarded

Ebola health care workers in Guinea (European Commission-ECHO/USIAD)

31 October 2014. A biodefense unit of the U.S. Department of Defense awarded a contract to vaccine maker Profectus BioSciences Inc. for development and testing of a vaccine protecting against the two major Ebola strains and related Marburg viruses. The $9.5 million contract with the Baltimore . . . → Read More: Ebola-Marburg Vaccine Development, Testing Contract Awarded

Clinical Trial to Test Safety of MRSA Drug Candidate

Scanning electron micrograph image of MRSA bacteria (Janice Haney Carr, Centers for Disease Control and Prevention)

Enanta Pharmaceuticals, a biotechnology company in Watertown, Massachusetts, is starting an early-stage clinical trial of an antibiotic to treat methicillin-resistant Staphylococcus aureus or MRSA infections. The drug, code-named EDP-788, is being developed under a contract with National Institute . . . → Read More: Clinical Trial to Test Safety of MRSA Drug Candidate

NIH Funding Further Marburg Virus Therapy Development

Marburg virus (U.S. Centers for Disease Control and Prevention)

BioCryst Pharmaceuticals Inc., a developer of drugs for infectious and rare diseases in Durham, North Carolina, says National Institutes of Health (NIH) is continuing its contract with the company to develop a treatment for Marburg virus, the cause of a rare but dangerous tropical disease. . . . → Read More: NIH Funding Further Marburg Virus Therapy Development

Contract Awarded for Influenza Vaccine and Immune Booster

H1N1 virus (U.S. Centers for Disease Control)

NanoBio Corporation in Ann Arbor, Michigan received a new contract from National Institute of Allergy and Infectious Diseases, part of National Institutes of Health, for development of a pandemic influenza vaccine and adjuvant to boost the immune response of that vaccine. The initial contract value is $5.5 . . . → Read More: Contract Awarded for Influenza Vaccine and Immune Booster

Fuel Cells for Refrigerated Trucks Under Development

A project combining the efforts of Pacific Northwest National Laboratory (PNNL) in Richland, Washington with two fuel cell manufacturers is developing fuel cells to power the refrigeration units in refigerated trucks. The companies — Nuvera Fuel Cells in Billerica,, Massachusetts and Plug Power Inc. in Latham, New York — each received a $650,000 matching contract . . . → Read More: Fuel Cells for Refrigerated Trucks Under Development

FDA Funds Organ-on-Chip to Test Radiation Disease Treatments

Gut-on-a-chip (Wyss Institute, Harvard University)

The U.S. Food and Drug Administration awarded a contract to a Harvard University lab for simulated organ devices to test radiation disease countermeasures. The $5.6 million award will fund the work of Harvard’s Wyss Institute for Biologically Inspired Engineering from FDA’s research and development program on regulatory science and . . . → Read More: FDA Funds Organ-on-Chip to Test Radiation Disease Treatments