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Yom Kippur 5776

23 September 2015. We’ll be observing Yom Kippur today, the day of atonement and holiest day in the Jewish calendar. Regular posting will resume tomorrow.

In th meantime, here’s Brazilian gospel singer Leonardo Goncalves with his version of the haunting Hebrew prayer for Yom Kippur, Avinu Malkeinu. (Hat tip: J.J. Goldberg, Jewish Daily Forward)

. . . → Read More: Yom Kippur 5776

Clinical Trial Underway Testing Cancer Surgery Aid

Cedars-Sinai Medical Center. Los Angeles, California (cedars-sinai.edu)

22 September 2015. A clinical trial is enrolling patients with soft tissue sarcoma to test a synthetic peptide that illuminates cancer cells to make them more easily removed during surgery. The early-stage study is testing the safety of the peptide made by Blaze Bioscience Inc. in . . . → Read More: Clinical Trial Underway Testing Cancer Surgery Aid

Virus Particles Rebuilt to Boost Immunotherapies

Portion of virus’s outer protein coat cut away to reveal virus contents (Public Domain Images)

22 September 2015. Engineers at Stanford University redesigned a hepatitis virus from the inside out to make it a better vehicle to stimulate the immune system for treating disease. The team led by chemical and bioengineering professor James . . . → Read More: Virus Particles Rebuilt to Boost Immunotherapies

Regeneron to Develop Antibody Therapy for Ebola

Scanning electron micrograph shows Ebola virus budding on monkey kidney cells (Defense.gov)

21 September 2015. Regeneron Pharmaceuticals Inc. received a contract from the U.S. Department of Health and Human Services to develop an engineered antibody designed to treat Ebola infections. The initial $17 million contract from HHS’s Biomedical Advanced Research and Development Authority . . . → Read More: Regeneron to Develop Antibody Therapy for Ebola

3-D Printed Guide Devised to Regrow Nerve Fibers

3-D printed nerve regeneration guide implanted in a rat (University of Minnesota College of Science and Engineering)

18 September 2015. Researchers from medical and engineering faculties at five universities in the U.S. developed a technique combining three-dimensional printing with tissue regeneration to grow new peripheral nerves in lab rats. The team led by . . . → Read More: 3-D Printed Guide Devised to Regrow Nerve Fibers

Optical Device IDs Healthy, Cancerous Tissue in Surgery

Pathologist slide image of breast cancer cells (Cecil Fox, National Cancer Institute)

18 September 2015. An engineering and medical team at University of Illinois in Champaign designed a surgical tool that identifies and discriminates between healthy and cancerous tissue in real time when removing tumors. Researchers led by engineering professor Stephen Boppart published . . . → Read More: Optical Device IDs Healthy, Cancerous Tissue in Surgery

Immunotherapy Shown to Clear Some Cervical Lesions

Cornelia Trimble (Johns Hopkins University)

17 September 2015. A clinical trial testing a vaccine designed to clear up cervical lesions or sores before they become cancerous, found women receiving the vaccine eradicated more of these lesions than those receiving a placebo. Results of the intermediate-stage trial, funded by Inovio Pharmaceuticals Inc. that makes . . . → Read More: Immunotherapy Shown to Clear Some Cervical Lesions

Allied Minds Forming Space Signaling Company

Small satellites in low-earth orbit (NASA.gov)

17 September 2015. Allied Minds, a research commercialization company in Boston, is forming a new enterprise harnessing space satellites to detect wireless signals from earth for maritime, emergency, and commercial applications. The company, HawkEye 360 Inc., is licensing research on radio-frequency communications from Virginia Polytechnic Institute and . . . → Read More: Allied Minds Forming Space Signaling Company

Platelet-Like Nanoparticles Boost Therapeutic Effects

Red blood cells held together with platelets, in blue, and fibrin, in yellow. (NIH.gov)

16 September 2015. Engineers and medical researchers at University of California in San Diego designed biocompatible nanoparticles disguised as blood platelets, which they found increased the particles’ targeting and medicinal effects. The team led by engineering faculty Liangfang Zhang . . . → Read More: Platelet-Like Nanoparticles Boost Therapeutic Effects

Spin-Off Formed to Develop Brain Disorder Therapies

(Arthur Toga, UCLA/NIH.gov)

16 September 2015. A new enterprise developing biologic therapies for disorders of the brain and nervous system is underway, spun-off from the acquisition in July 2015 of Naurex Inc. by the pharmaceutical company Allergan plc. The new company, Aptinyx Inc. in Evanston, Illinois will have many of the same team . . . → Read More: Spin-Off Formed to Develop Brain Disorder Therapies