Bodkin Design & Engineering in Wellesley Hills, Massachusetts, with Boston University and Zoíray Technologies, also in Boston, have developed a commercial instrument based on the partners’ basic research. The product, the Spectral Reflectance Imaging Biosensor (SRIB), is a multiplexed immunoassay platform for life science research and clinical diagnostics.
Immunoassays are chemical tests used to detect or quantify a specific substance, called an analyte, in a blood or body fluid sample — e.g., blood, urine, or saliva — using an immunological reaction. Zoíray’s technology enables many immunoassays to be multiplexed on one disposable chip.
SRIB’s design combines a tunable laser, high resolution camera, fluidics, and digital control. The system automatically conducts specimen delivery, reagent introduction, optical interrogation, specimen disposal and data analysis, in a table top unit.
The system operates by loading a biochip containing active proteins into the device. The user then prompts the system to deliver the specimen and reagents to the reaction flow cell, where incubation takes place. The sample is optically probed with the laser and evaluated. Thousands of interactions are captured simultaneously and analyzed using the built-in camera and computer.
Bodkin Design & Engineering is a maker of custom-engineered optical instruments. Zoíray Technologies produces multiplexed immunoassays for research and diagnostics.
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