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AI-Designed Cancer Vaccine Shown to Act Against Melanoma

T-cells and cancer cells

Results of a small clinical trial show most patients with melanoma receiving a personalized therapeutic vaccine with an approved immunotherapy reduced at least some of their tumors. . . . → Read More: AI-Designed Cancer Vaccine Shown to Act Against Melanoma

Low-Dose Oral Film Reduces Mental Disorder Agitation

Depression

Interim results from a clinical trial show a drug given as a dissolvable oral film in a lower dose reduces agitation in people with bipolar disorder and schizophrenia. . . . → Read More: Low-Dose Oral Film Reduces Mental Disorder Agitation

$60M Challenge Seeks Biomarkers, Models to Counter Aging Stress

Older cyclist on a bicycle path

A new challenge competition seeks biomarkers, models, and clinical tests of the factors behind responses to stress conditions in human aging that can stave off frailty or death. . . . → Read More: $60M Challenge Seeks Biomarkers, Models to Counter Aging Stress

Measles-Rubella Patch Vaccine Shown Effective as Injection

Child receiving vaccine patch

A clinical trial shows a peel-and-stick patch device is as effective as a standard syringe injection in delivering a vaccine that protects against measles and rubella. . . . → Read More: Measles-Rubella Patch Vaccine Shown Effective as Injection

Collaboration to Boost Rare Disease Clinical Trials

Network pointer

An organization seeking new uses for today’s drugs and a contract research company aim to increase the number of clinical trials for rare diseases testing already approved drugs. . . . → Read More: Collaboration to Boost Rare Disease Clinical Trials

Trial Underway Testing Psychedelic Drug for Depression

Sonoran desert toad

The first participant in a clinical trial received a dose of a psychedelic therapy, assessing the experimental compound in people with treatment resistant depression. . . . → Read More: Trial Underway Testing Psychedelic Drug for Depression

DNA Test Detects Early Bladder Cancer in Urine

DNA illustration

A genomic analysis of urine samples is shown to predict the most common form of bladder cancer years before symptoms appear. . . . → Read More: DNA Test Detects Early Bladder Cancer in Urine

Light-Activated Therapy Improves Vision in Inherited Disease Trial

Retinal gene therapy

A clinical trial shows a light-activated protein from an injected gene improves visual abilities in people with advanced retinitis pigmentosa, an inherited eye disorder. . . . → Read More: Light-Activated Therapy Improves Vision in Inherited Disease Trial

Low-Dose Covid-19 Vaccine Generates Strong Immune Response

Exosome illustration

Ultra-low quantities of an experimental Covid-19 protein vaccine delivered in synthetic cell components are shown in lab animals to generate strong immune responses. . . . → Read More: Low-Dose Covid-19 Vaccine Generates Strong Immune Response

Real World Evidence Shown to Emulate Some Clinical Trials

Data pointing finger

A study of insurance claims records matching the design of randomized clinical trials shows claims data can in some cases resemble clinical trial results to make causal inferences. . . . → Read More: Real World Evidence Shown to Emulate Some Clinical Trials