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Ebola Monitoring System Devised with Genome Sequencing

Ebola genome sequencing lab in Guinea (European Mobile Lab)

3 February 2016. An international team of scientists and engineers designed a mobile system using a hand-held genome sequencing device that provided real-time monitoring of the Ebola outbreak in West Africa in 2015. Researchers led by microbiologists Nicholas Loman and Joshua Quick at University . . . → Read More: Ebola Monitoring System Devised with Genome Sequencing

Regeneron to Develop Antibody Therapy for Ebola

Scanning electron micrograph shows Ebola virus budding on monkey kidney cells (Defense.gov)

21 September 2015. Regeneron Pharmaceuticals Inc. received a contract from the U.S. Department of Health and Human Services to develop an engineered antibody designed to treat Ebola infections. The initial $17 million contract from HHS’s Biomedical Advanced Research and Development Authority . . . → Read More: Regeneron to Develop Antibody Therapy for Ebola

Point-of-Care Ebola Test Found Accurate in Field Test

Woman being evaluated at an Ebola clinic in Sierra Leone (Rebecca Rollins, Partners In Health)

26 June 2015. A commercial point-of-care test detecting Ebola virus in the blood of a patient was shown in a field test in Sierra Leone to be as accurate as tests sent to remote labs for analysis. Results . . . → Read More: Point-of-Care Ebola Test Found Accurate in Field Test

FDA Approves Pediatric HIV Drug Formulation

Scanning electron micrograph of HIV particles infecting a human T cell (NIH.gov)

5 June 2015. The U.S. Food and Drug Administration approved an application for a current HIV drug formulated to better treat infections in infants and young children, especially in limited resource regions. The formulation is a combination of lopinavir and ritonavir . . . → Read More: FDA Approves Pediatric HIV Drug Formulation

Smartphone Vision App Found Accurate as Clinic Test

Visual acuity test on smartphone (peekvision.org)

29 May 2015. An inexpensive smartphone-based test was found to measure visual acuity as well as the familiar standard eye chart used in clinics. The team that developed the Portable Eye Examination Kit or Peek at the London School of Hygiene and Tropical Medicine and other institutions . . . → Read More: Smartphone Vision App Found Accurate as Clinic Test

Trial Testing 3-Drug Combo for Drug Resistant TB

Tuberculosis bacteria (DoE.gov)

14 May 2015. A new clinical trial is underway in South Africa testing a regimen of three drugs to treat extensively drug-resistant tuberculosis, a form of the disease that does not respond to normal or even back-up treatments. The trial is sponsored by Global Alliance for TB Drug Development, or . . . → Read More: Trial Testing 3-Drug Combo for Drug Resistant TB

Intermediate Trial Shows Ebola Vaccines Safe

Scanning electron micrograph of Ebola virus (National Institute of Allergy and Infectious Diseases)

27 March 2015. An intermediate-stage clinical trial in Liberia testing two new vaccines to prevent Ebola infections, shows the vaccines appear to be safe, allowing for larger-scale assessments. Initial results of the trial were reported yesterday by National Institute of . . . → Read More: Intermediate Trial Shows Ebola Vaccines Safe

U.S., Canada Authorities OK Biotech Ebola Treatments

Ebola health care workers in Guinea (European Commission-ECHO/USIAD)

23 September 2014. Tekmira Pharmaceuticals Corp. says the U.S. Food and Drug Administration approved the company providing its experimental therapy for people with suspected or confirmed Ebola infections. The Vancouver, British Columbia biotechnology company says approval of its therapy called TKM-Ebola is part of a . . . → Read More: U.S., Canada Authorities OK Biotech Ebola Treatments

Small Business Grant Funds Point-of-Care Sickle Cell Test

Sickle cell test sample (A. J. Kumar, Harvard University)

22 September 2014. A Cambridge, Massachusetts diagnostics company received a Small Business Innovation Research (SBIR) grant to develop a simple point-of-care test for sickle cell disease, a genetic blood disorder affecting a large percentage of people of African origin. The $225,000 grant from National . . . → Read More: Small Business Grant Funds Point-of-Care Sickle Cell Test

Ebola Vaccine Safety Trials Scheduled in U.S., U.K., Africa

Ebola health care workers in Guinea (European Commission-ECHO/USAID)

28 August 2014. Early-stage clinical trials testing the safety of new vaccines to protect against the Ebola virus are scheduled to begin as early as next week at sites in the U.S., United Kingdom, Mali, and The Gambia in West Africa. The vaccines are being . . . → Read More: Ebola Vaccine Safety Trials Scheduled in U.S., U.K., Africa